Interactive Case Study - 10- October 2024

83-year-old with diffuse abdominal telangiectases

Mekaleya Tilahun, B.S.

Gail Jacoby, M.D., F.A.A.D.

Thaddeus Mully, M.D., F.A.A.D

An 83-year-old man presented with a six-month history of asymptomatic telangiectases on the abdomen. His past medical history included hypothyroidism, hypercholesterolemia, atherosclerotic disease, atrial fibrillation, basal cell carcinoma, and rosacea. He had no personal or family history of a bleeding diathesis. Physical examination revealed a widespread network of blanching telangiectatic mats on the anterior abdomen. There was no involvement of other areas including mucous membranes. Histopathologic findings are shown in Figures 1-3.

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Which of the following is the best diagnosis?

Cutaneous collagenous vasculopathy

Angioma serpiginosum

Generalized essential telangiectasia

Telangiectasia macularis eruptiva perstans

Hereditary hemorrhagic telangiectasia

Salama S, Rosenthal D. Cutaneous collagenous vasculopathy with generalized telangiectasia: an immunohistochemical and ultrastructural study. J Cutan Pathol. 2000 Jan;27(1):40–8.
Burdick LM, Losher S, Somach SC, Billings SD. Cutaneous collagenous vasculopathy: a rare cutaneous microangiopathy. J Cutan Pathol. 2012;39(8):741–6.
Grossman ME, Cohen M, Ravits M, Blume R, Magro CM. Cutaneous collagenous vasculopathy: A report of three cases. J Cutan Pathol. 2022;49(5):491–5.
Stavrou C, Uthayakumar A, Calonje JE, Bunker CB. Cutaneous collagenous vasculopathy. BMJ Case Rep CP. 2021 Mar 1;14(3):e241434.
Echeverría B, Sanmartín O, Botella-Estrada R, Vitiello M. Cutaneous collagenous vasculopathy successfully treated with pulsed dye laser. Int J Dermatol. 2012;51(11):1359–62.
Brady BG, Ortleb M, Boyd AS, Powers J. Cutaneous Collagenous Vasculopathy. J Clin Aesthetic Dermatol. 2015 Nov;8(11):49–52.
Patel N, Mohammadi A, Rhatigan R. A Comparative Analysis of Mast Cell Quantification in Five Common Dermatoses: Lichen Simplex Chronicus, Psoriasis, Lichen Planus, Lupus, and Insect Bite/Allergic Contact Dermatitis/Nummular Dermatitis. Int Sch Res Not. 2012 Feb 1;2012:e759630.
Huang A, Desai A, Brinster N, Marmon S. Telangiectasia macularis eruptiva perstans in the presence of liver cirrhosis. JAAD Case Rep. 2020 May 1;6(5):438–40.

Acknowledgements

Author Profiles

Mekaleya Tilahun, B.S.

UCSF School of Medicine

Mekaleya Tilahun is a fourth-year medical student at UCSF and is currently on her research year conducting qualitative research with the UCSF Department of Dermatology and Department of OB/GYN. Her primary research interests include health and healthcare disparities, pigmentary disorders and global health.

Gail Jacoby, M.D., F.A.A.D.

Sequoia Hospital in Redwood City

Dr. Jacoby graduated from Jefferson Medical College in Philadelphia, interned in Internal Medicine at Thomas Jefferson University Hospital and did her dermatology at the University of California -San Francisco Medical Center. She has been in the practice of Dermatology for over 40 years serving as an assistant clinical professor of dermatology and currently practicing in San Carlos, CA, for over 25 years.

Thaddeus Mully, M.D., F.A.A.D

UCSF Department of Dermatopathology

Dr. Thaddeus Mully is a professor of Pathology in the department of Dermatopathology at the University of California, San Francisco (UCSF). He completed his pathology residency at Yale University and UCSF and his dermatopathology fellowship at New York University (NYU). He served as faculty at NYU and the University of Pittsburgh and was a member of a large private practice in Cambridge, Massachusetts before returning to UCSF.

Question:

Interactive Case Study - 10- October 2024

Acknowledgements

Author Profiles

83-year-old with diffuse abdominal telangiectases

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