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Interactive Case Study - 05- May 2025






Patterson JW. Weedon’s Skin Pathology. Elsevier; 2021:825-880, 951-1065.
Au RTM, Bundele MM. Endocrine mucin-producing sweat gland carcinoma and associated primary cutaneous mucinous carcinoma: Review of the literature. Journal of Cutaneous Pathology. 2021;48(9):1156-1165. doi:https://doi.org/10.1111/cup.13983
Agni M, Raven ML, Bowen RC, et al. An Update on Endocrine Mucin-producing Sweat Gland Carcinoma: Clinicopathologic Study of 63 Cases and Comparative Analysis. Am J Surg Pathol. Aug 2020;44(8):1005-1016. doi:10.1097/pas.0000000000001462
Ravi PY, Walsh NM, Archibald C, Pasternak S. Endocrine Mucin-Producing Sweat Gland Carcinoma: Emerging Evidence of Multicentric Cutaneous Origin and Occasional Concurrence With Analogous Breast Tumors. The American Journal of Dermatopathology. February 15, 2022 2022;44(5):321-326. doi:10.1097/DAD.0000000000002132
Chung J, Rico-Castillo J, Sebastiano C, Lee JB. Expression of p40 in Primary Cutaneous Mucinous Carcinoma Versus Primary Mucinous Carcinomas of the Breast and Colon. The American Journal of Dermatopathology. 2021;43(12):e175-e180. doi:10.1097/dad.0000000000001973
Acknowledgements
Acknowledgements
Jarett Casale, DO - Dermatology PGY-4 - Campbell University at Sampson Regional Medical Center
Jesse Dewey, DO - Dermatology PGY-3 - Campbell University at Sampson Regional Medical Center
Alice Roberts MD, PhD – Dermatopathologist – Eastern Virginia Medical School
Author Profiles

Parker Adams, BS – MS2
Eastern Virginia Medical School
Parker Adams is a second-year medical student at Eastern Virginia Medical School. Originally from Raleigh, North Carolina, he attended North Carolina State University where he graduated with a bachelor’s degree in biological sciences. He enjoys spending time exploring his home in Norfolk, Virginia, with his wife and their dog. He aspires to be a dermatologist.
Melissa Munoz-Bishop, MD
Greensboro Pathology Associates/Aurora Diagnostics
Dr. Munoz-Bishop attended medical school at the Universidad Autonoma de CentroAmerica in Costa Rica. She completed her residency in Anatomic and Clinical Pathology at Drexel University Hospital in Philadelphia, followed by a Surgical Pathology fellowship at Emory University Hospital in Atlanta. She then completed her Dermatopathology fellowship at Roger Williams Medical Center in Rhode Island.

Adam Ingraffea, MD
Cary Skin Center
Adam Ingraffea, MD, graduated from Boston University with a B.S. in Chemistry. He studied medicine at the Ponce School of Medicine in Ponce, PR, where he graduated as valedictorian and was inducted into the AOA Honor Society. He completed his dermatology residency at Boston University/Roger Williams Medical Center in Providence, Rhode Island. He completed his Mohs surgery fellowship at the University of Cincinnati College of Medicine, where he then went on to serve as Assistant Professor of Dermatology and Associate Program Director for both the dermatology residency and Mohs surgery fellowship programs. He is the author of 18 peer-reviewed papers as well as multiple book chapters.
Question:
54-year-old Man with a Painful Nodule on the Left Zygomatic Arch
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